Both teams rested some key players in their domestic leagues ahead of this clash.

In terms of momentum, Juventus comes in on a high after securing a late 2-1 win against Como, while PSV suffered a surprising 1-1 draw against Willem II, a result that dented their position in the Eredivisie.

This will be a tough match for both sides, but we believe Juventus holds the edge over the two-leg fixture for several reasons.

Defensively, Juventus is more solid without possession, whereas PSV has struggled at the back, conceding twice against both Red Star Belgrade and Liverpool's B team. Their recent head-to-head in the group stage saw Juventus claim a comfortable 3-1 victory, despite PSV having a slight possession advantage (54%). Juventus also registered an impressive 2.57 xG without dominating the ball.

In that match, PSV trailed 3-0 until a late consolation goal. This time, they are further weakened by the absence of three key players—two of them in defense.

Missing from the squad are starting right-back Ledezma, central defender Boscagli, and influential attacking midfielder Tillman, all sidelined due to injuries. These absences could make it even harder for PSV to contain Juventus.